Chicago Fire has always been more than just a show about firefighters; it’s a deep dive into the lives, loves, and devastating losses of the brave men and women of Firehouse 51. For over a decade, we’ve laughed with them, cheered for them, and most certainly, cried with them. These characters aren’t just faces on a screen; they’re family, making every setback, every goodbye, feel incredibly personal.

Get ready to grab some tissues, because we’re looking back at some of the most heart-shattering moments that had fans reaching for the Kleenex and hitting the pause button, just to compose themselves.

1. Leslie Shay’s Devastating Death

Perhaps the most impactful death in the show’s history, Shay’s death in the Season 3 premiere hit like a ton of bricks. Her vibrant personality and her incredible bond with Dawson and Severide made her loss feel truly monumental. It was a stark reminder that no one is truly safe, and the emotional fallout reverberated for seasons. Even now, thinking about it stings.

2. Otis’s Heroic Sacrifice

When Brian “Otis” Zvonecek died during the mattress factory fire in the Season 8 premiere, the silence in the firehouse felt deafening. Otis was the heart and soul of 51’s quirky humor, and his final words to Cruz, “I made it,” were utterly crushing. His memorial was one of the most poignant scenes, cementing his legacy and leaving a permanent hole in the team.

3. Casey’s Emotional Farewell

Saying goodbye to Matthew Casey, one of the original and foundational characters, was tough. His departure to Oregon to care for Darden’s boys in Season 10 felt right for his character arc, but it didn’t make it any easier to watch. His final scenes with Brett and Severide were filled with so much love and unspoken emotion, leaving us with a bittersweet ache.

4. Herrmann’s Near-Fatal Stabbing

Seeing Christopher Herrmann, the grumpy but lovable patriarch of 51, get stabbed in Molly’s in Season 4 was a terrifying moment. For a character who brings so much light and laughter, watching him fight for his life was incredibly stressful. The relief when he pulled through was immense, but the memory of that vulnerability remains.

5. Cruz’s PTSD After the Mattress Factory Fire

While Otis’s death was heartbreaking, Joe Cruz’s struggle with PTSD in the aftermath was equally gut-wrenching. His guilt and trauma were palpable, and watching him try to cope with the loss of his best friend was a raw and honest portrayal of grief. It highlighted the unseen battles firefighters face.

6. Gabby Dawson’s Departure

Gabriela Dawson’s decision to leave Chicago for Puerto Rico in Season 7 was a tough pill to swallow, especially for “Dawsey” fans. Her relationship with Casey was central to the show for so long, and her departure felt like the end of an era. It was a complex, realistic exit, but it still hurt to see her go.

7. Severide’s Struggle with His Father’s Death

While Benny Severide wasn’t always the easiest character to love, his sudden death in Season 7 deeply affected Kelly. Watching Severide grapple with the loss of his father, the man who shaped him, revealed a vulnerable side to the often-stoic lieutenant. His grief was palpable and truly heartbreaking.

8. Stella Kidd’s Near-Miss at the Inferno

There have been countless close calls on the job, but Stella Kidd’s life hanging in the balance during a massive inferno (like the apartment building fire in Season 9 where she was trapped) always gets our hearts racing. Knowing how much she means to Severide and the rest of 51 makes these moments particularly agonizing.

9. Boden’s Emotional Loss of His Grandfather

Chief Boden is the rock of Firehouse 51, and seeing him vulnerable is rare. When Boden dealt with the death of his beloved grandfather in Season 4, it was a poignant reminder of his deep family roots and the personal sacrifices he makes. It was a quiet, dignified grief, but no less impactful.

10. Brett’s Unanswered Questions About Her Birth Mother

The storyline involving Sylvie Brett’s search for and eventual meeting with her birth mother (and then her mother’s subsequent illness) was filled with emotional highs and lows. Watching Brett navigate this complex family dynamic, only to face more heartache, was a difficult journey for fans who had invested so much in her happiness.